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GIARDIA
MORPHOLOGY
• Characteristic trophozoites are pear-shaped, binucleate, faintly basophilic organisms seen in between villi with no associated inflammation
• Sometimes mild villous blunting and intraepithelial lymphocytes can be seen
• Look like “falling leaves” in the bowel lumen
OTHER HIGH YIELD POINTS
· Most common protozoa infection in the United States
· Usually acquired from contaminated water; can be fecal-oral and sexually transmitted
• More common in children, with travel, and immunocompromised
• Causes diarrhea (unclear pathogenesis), often watery and foul-smelling
• Infection can be chronic in immunocompromised
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